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Axiom™ Biobank Genotyping Array

The Axiom™ Biobank Genotyping Array was designed by and for thought leaders in the human genetics community for high-throughput, high-value genotyping of large sample cohorts to explore the genetics of complex diseases and translational research with a single comprehensive low-cost solution. This array contains one 96-array plate that allows for genome-wide genotyping of large sample collections such as those screened at biobanks, genome centers, and core labs.

GWAS

  • Intelligent marker selection enables imputation of millions of additional SNPs
  • The genomic content module of each array is optimized for specific populations and is customizable to any 1000 Genomes population study by adding additional markers of your choosing
  • Immune function, including content covering the major histocompatibility complex (MHC), human leukocyte antigen (HLA), and killer-cell immunoglobulin-like receptors (KIR)

Pharmacogenomic markers

  • Markers were selected to represent phases of absorption, distribution, metabolism, and excretion (ADME)

Inflammation and HLA

  • Contains markers with evidence for association with autoimmune and inflammation
  • Covers variants in genes in the HLA and KIR regions known to be important in immune response

Exome

  • Rare, non-synonymous coding SNPs and indels in protein coding regions of the genome
  • A majority of variants are rare with minor allele frequency (MAF) <1%
  • Newly discovered loss-of-function content
  • SNPs and indels identified from a sequencing initiative of 26,000 individuals
  • Known disease-causing mutations

eQTLs

  • Markers that have known associations to RNA expression traits
  • Captures unique eQTLs contained in the NCBI Genotype-Tissue Expression (GTEx) eQTL database, GEUVIDAS project, and several other discovery projects

Human disease

  • Blood phenotypes
  • Cancer common variants
  • Cardiometabolic

Choose your content

  • Order the pre-designed array and customize it with markers of your choice
  • Custom markers may be de novo or selected from the Axiom Genomic Database of genotype-tested markers

Array format: 96-array plate
DOWNLOADABLE BROCHURE:
Axiom Biobank Genotyping Arrays
Axiom Biobank Genotyping Solution

Category:
Molave Trading
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