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Oncomine Precision Assay GX

Next-generation oncology solution
The Oncomine Precision Assay on the Ion Torrent Genexus System is a next-generation genomic profiling solution that can allow every laboratory to deliver a genomic profile with a one-day, hands-free workflow. Now labs can employ a hands-off workflow to detect key biomarkers such as EGFR, ALK, BRAF, ROS1, NTRK, RET, or ERBB2 from formalin-fixed paraffin-embedded (FFPE) tissue or liquid biopsy specimens in one day.
Mutation, CNV, and fusion variant types across 50 key genes such as EGFR, ALK, BRAF, ROS1, RET, KRAS, PIK3CA, and ERBB2, among others
One-day, hands-free workflow with only two touch points and 10 minutes of hands-on time
Only 10 ng of DNA/RNA required, allowing for more samples to be tested
Compatible with FFPE tissue as well as liquid biopsy samples

FusionSync detection technology
There are a number of known and recurrent fusion isoforms that constitute a majority of the fusions detected. Having specific designs for these isoforms is important to maximize detection, even in challenging situations when sample input or transcript levels are low. The optimized, synced design of the Oncomine Precision Assay enables comprehensive, sensitive fusion detection (including novel fusions in select driver genes) at low transcript or input levels.
Targeted known-fusion detection for the most common and prevalent fusion isoforms (e.g., EML4 -ALK, ETV6-NTRK3, KIF5B-RET, etc.)
Non-targeted detection of novel fusion combinations of targeted driver and partner genes
Novel fusions detection by proprietary exon tiling imbalance method