Catalog number: A38262
The Ion AmpliSeq Exome RDY Kit enables the fastest and simplest method of exome enrichment, now even easier with oligo pools for ultra-high multiplex PCR exome enrichment dried down in a 96-well plate. With half the number of target amplification pipetting steps compared to the original protocol and the elimination of small pipetting volumes, exome libraries can now be produced with unparalleled ease in under six hours with less than 50 minutes of hands-on time. Also, the Ion AmpliSeq Exome RDY Kit is compatible with the Ion Library Equalizer Kit for ease in library normalization. Leveraging the ultra-high multiplex PCR approach of Ion AmpliSeq technology with template preparation on the Ion Chef System and sequencing on an Ion Proton or Ion S5 System, the Ion AmpliSeq Exome RDY Kit allows for rapid sequencing of key exonic regions of the genome, going from DNA to variants in just two days.
The Ion AmpliSeq Exome RDY Kit 1×8 configuration includes the following components for eight exomes (two exomes per Ion PI v3 chip or Ion 540 Chip, and four exomes per Ion 550 Chip):
Ion AmpliSeq Exome RDY panel: dried down oligo pools/primers in one 96-well plate with all eight rows filled (1×8), for ultra-high multiplex PCR enrichment of the exonic regions of the genome
Ion AmpliSeq Library Kit Plus (8 exomes) for robust library preparation of Ion AmpliSeq Exome libraries using Ion AmpliSeq technology
The Ion AmpliSeq Exome RDY Kit enables you to:
Simplify exome enrichment through the combination of dried-down primers and the Ion AmpliSeq workflow, with less than one hour of hands-on time and less than six hours total time
Accelerate your disease research with rapid exome sequencing—DNA to variants in just two days
Access affordable exome sequencing—no need to wait and batch dozens of samples or otherwise spend the high price of a lower-throughput run
Maximize sequencing efficiency due to high performance specifications—designs covering >97% of the Consensus Coding Sequences (CCDS), >90% base on-target, and >90% coverage uniformity
Identify annotated, filtered variants without bioinformatics expertise through fully integrated analysis with Torrent Suite and Ion Reporter software
Nuclear magnetic resonance (NMR) spectroscopy is a very powerful and precise analytical tool used to determine the structure of compounds, as well as to detect and quantify protein-ligand interactions that provides insights into molecular structures and affinity. The technology’s exceptional sensitivity and robustness enables it to detect even weak intermolecular interactions in solution phase, making it an invaluable tool in drug discovery and development. The analytical process does not require extensive optimizations, as the only prerequisite for NMR experiment to proceed (for structure determination or binding strength measurement) is the solubility of the target protein and/or the small molecule (ligand) in a selected solvent, making it an easily accessible technique.
Indeed, Bruker provides the world’s most accessible and easy-to-operate suite of NMR systems. With its user-focused technology, NMR confidence can be seamlessly and affordably integrated into laboratory workflows without compromising performance. Through Bruker’s partnership with Molave Trading Inc. and the University of San Agustin (USA), natural drug discovery reaches new heights in the country upon the installation of the Bruker Ascend 600 MHz Cryoprobe NMR Spectrometer in USA’s Magnetic Resonance Facility in Iloilo City. This milestone set a new standard as the first and only of its kind in the Philippines, and the 4th country in the ASEAN region.
In fact, the Bruker cryoprobe NMR spectrometer was extremely instrumental when a team of scientists from the University of San Agustin made a significant scientific breakthrough last February 21, 2023. They published the discovery of a new bacterial species from the Tubbataha Reefs Natural Park, a UNESCO World Heritage Site in Sulu Sea, which produces natural compounds with antibiotic and anticancer properties. NMR was one of the primary tools utilized to profile and confirm the structure of rare chlorine-containing compounds from this novel bacterial strain. The study was published in the journal Microbiology Spectrum from the American Society for Microbiology. Truly, a highlight of Filipino research excellence!
A sign of a healthy community is its simultaneous ability to preserve and invent its culture – to look back in history while developing new expressions for the present time. Much of our history is contained in artworks, documents, artifacts and other cultural heritages. As these objects are of utmost significance, preserving them has become a science-based discipline that entails meticulous cleaning, repairing, re-assembling as well as toning to blend with the original object. Further research and analysis are also done to identify material composition, effects of aging, and extent of damage caused by environmental pollution.
The Agilent Fourier Transform Infrared (FTIR) Spectrometer is used to analyze organic substances in valuable sculptures and artefacts without introducing significant destruction to the material. With innovative sampling technology, it can analyze objects that are too large, too valuable or too remote to measure with conventional spectrometers. Overcoming these challenges further preserves the integrity and authenticity of these historical objects; thus enriching the country’s heritage for future generations to come.
Everybody loves burgers. It is the harmonious relationship of two lightly toasted buns topped with roasted sesame seeds embracing a perfectly seared beef patty that’s rich brown on the outside and soft pink on the inside. Add to that a generous spread of mayonnaise, crisp lettuce and freshly sliced tomato. But the star of the show is the beef. It must be of top quality – with just the right amount of meat and fat to give it its juiciness, just the right amount of moisture and just the right amount of salt to give shape to its flavor.
The Foss FoodScan Meat Analyser helps your favorite burger joints produce the perfect beef patties for their burgers. Each patty is analyzed for its fat, moisture, protein, and salt content to make its shape, color, texture, and aroma consistent throughout wherever they may be served. So whether you’re eating a burger in Manila or in Davao, you can taste the same combination of textures and flavors that you gladly enjoy in your favorite burger.
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