Axiom Maize Genotyping Array was designed by the AgroClustER Synbreed (funded by the German Ministry of Education and Research, BMBF) through a collaboration led by Professor Chris-Carolin Schön, Dr. Eva Bauer, and Sandra Unterseer (Technische Universität München, Germany), and Dr. Georg Haberer and Michael Seidel (Helmholtz Zentrum München, Germany) through Affymetrix Expert Design Program. The array interrogates 616,201 carefully selected polymorphic variants to represent the global diversity in the maize genome.
The array overcomes specific challenges caused by a high content of repetitive elements, high genomic and structural diversity, and low linkage disequilibrium (LD) in different cultivars. The SNPs on the array were first discovered through resequencing in a panel of 30 inbred lines that represented global diversity. The array was validated by using a diverse set of European, US, and tropical/semi-tropical lines from various Dent and Flint gene pools.
Features of Axiom Maize Genotyping Array:
- Comprehensive content – 616,201 variants including 609,442 SNPs and 6,759 small insertion/deletion variants
Applications of Axiom Maize Genotyping Array:
- Complex trait research –genetic diversity analysis, association mapping, genome-wide analysis and selection, haplotype structure in maize varieties, LD analysis, QTL mapping
- Molecular breeding – development of new inbred lines, genomic selection
Array format: 96-array plate
Axiom™ Maize Genotyping Array
Axiom Genotyping Arrays for Agrigenomics